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Published: 2021-01-01

Editorial

Call for emergency action to limit global temperature increases, restore biodiversity, and protect health

Lukoye Atwoli, Abdullah H. Baqui, Thomas Benfield, Raffaella Bosurgi, Fiona Godlee, Stephen Hancocks, Richard Horton, Laurie Laybourn-Langton, Carlos Augusto Monteiro, Ian Norman, Kirsten Patrick, Nigel Praities, Marcel Olde Rikkert, Eric J. Rubin, Peush Sahni, Richard Smith, Nicholas J Talley, Sue Turale, Damián Vázquez

Reviews

An insight into lung cancer: a comprehensive review exploring ALK TKI and mechanisms of resistance

Adela Patcas, Ana Florica Chis, Claudia Florentina Militaru, Ioana Roxana Bordea, Ruxandra Rajnoveanu, Ovidiu Florin Coza, Reem Hanna, Tamas Tiberiu, Doina Adina Todea
Trop-2 protein as a therapeutic target: A focused review on Trop-2-based antibody-drug conjugates and their predictive biomarkers

Semir Vranic, Zoran Gatalica
Perineural spread in head and neck malignancies: imaging findings - an updated literature review

Olga Medvedev, Mihaela Hedesiu, Anca Ciurea, Manuela Lenghel , Horatiu Rotar, Cristian Dinu, Rares Roman, Dragos Termure, Csaba Csutak
Role of dynamic contrast enhanced magnetic resonance imaging in the diagnosis and management of vascular lesions of the head and neck

Raluca Petea-Balea, Manuela Lenghel , Horatiu Rotar, Cristian Dinu, Simion Bran, Florin Onisor, Rares Roman, Simona Senila, Csaba Csutak, Anca Ciurea
Application of microfluidic chips in anticancer drug screening

Xin-yue Fan, Zhuo-fen Deng, Yan-yan Yan, Valerii E. Orel, Andrii Shypko, Valerii B. Orel, Donika Ivanova, Christian Pilarsky, Jing Tang, Zhe-Sheng Chen, Jian-ye Zhang

Biochemistry

Serum glial fibrillary acidic protein as a biomarker of brain injury in premature neonates

Dimitra Metallinou, Grigorios Karampas, Georgia Nyktari , Nicoletta Iacovidou , Katerina Lykeridou , Demetrios Rizos

Pathology

The effect of VEGF rs35569394 in esophageal cancer and response to chemotherapy

Zishan Wang, Chenwei Li, Xinjian Li, Jianguang Shi, Weijie Wu
EWSR1 rearrangement in papillary thyroid microcarcinoma is related to classic morphology and the presence of small-cell phenotype

Bozidar Kovacevic, Ana Caramelo, Vesna Skuletic, Snezana Cerovic, Catarina Eloy
Poorly differentiated clusters and tumor budding are important prognostic factors in colorectal carcinomas

Aura Jurescu, Adrian Văduva, Adelina Gheju
Inflammatory cells in the ascending aortic aneurysm in patients with type 2 diabetes versus patients with hypertension Aortic aneurysm inflammatory cell infiltration in diabetics

Aleksandra Milutinović, Ruda Zorc-Pleskovič

Molecular Biology

Clinical significance of miR-129-5p in patients with neonatal sepsis and its regulatory role in the LPS-induced inflammatory response

Meng Li, Xiaoyang Huang, Qingcui Zhuo, Jinghui Zhang, Xiuli Ju
Multidimensional study of cell division cycle-associated proteins with prognostic value in gastric carcinoma

Peixin Lu, Wen Cheng, Kexin Fang, Bin Yu
Long noncoding RNA FAM225B facilitates proliferation and metastasis of nasopharyngeal carcinoma cells by regulating miR-613/CCND2 axis

Weijun Dai, Yi Shi, Weiqi Hu, Chenjie Xu
Long noncoding RNA RP11-70C1.3 confers chemoresistance of breast cancer cells through miR-6736-3p/NRP-1 axis

Lansheng Zhang, Xia Zheng, Anqi Shen, Daojin Hua, Panrong Zhu, Caihong Li, Zhengxiang Han
Quercetin ameliorates testosterone secretion disorder by inhibiting endoplasmic reticulum stress through the miR-1306-5p/HSD17B7 axis in diabetic rats

Di Wang, Yan Li, Qian-qian Zhai, Yun-feng Zhu, Bei-yan Liu, Yun Xu
CircFOXM1 promotes the proliferation, migration, invasion, and glutaminolysis of glioblastoma by regulating the miR-577/E2F5 axis

Xuhui Fan, Meng Liu, Li Fei, Zhihui Huang, Yufeng Yan

Pharmacology

Resveratrol ameliorates neuronal apoptosis and cognitive impairment by activating the SIRT1/RhoA pathway in rats after anesthesia with sevoflurane

Qiaoyun Zhou, Yingfeng Deng, Xuelian Hu, Yinye Xu

Translational and Clinical Research

The value of routine measurement of serum calcitonin on insufficient, indeterminate, and suspicious thyroid nodule cytology

Muhammed Erkam Sencar, Sema Hepsen, Murat Çalapkulu, Hayri Bostan, Davut Sakiz, Ilknur Ozturk Unsal, Hakan Duger, Muhammed Kizilgul, Bekir Ucan, Tugba Taskin Turkmenoglu, Mustafa Ozbek, Erman Cakal
The prognostic significance of different proportion of signet-ring cells of colorectal carcinoma

Wei Chen, Huajun Cai, Kui Chen, Xing Liu, Weizhong Jiang, Shoufeng Li, Yiyi Zhang, Zhifen Chen, Guoxian Guan
Construction and validation of prognostic nomogram for metaplastic breast cancer

Yongfeng Li, Daobao Chen, Haojun Xuan, Mihnea P. Dragomir, George A. Calin, Xuli Meng, Meng Chen, Hongchuan Jin
Audiological and vestibular evaluations in vitiligo patients

Alessandra Manno, Annalisa Pace, Giannicola Iannella, Valeria Rossetti, Roberta Polimeni, Alessandro Milani, Salvatore Cocuzza, Antonino Maniaci, Giuseppe Magliulo
The long-term outcome and risk factors for precursor B cell acute lymphoblastic leukemia without specific fusion genes in Chinese children: experiences from multiple centers

Pinli Zou, Min Zhou, Jinquan Wen, Xin Liao, Yali Shen, Haiyan Liu, Lin Song, Jianwen Xiao
Six RNA binding proteins (RBPs) related prognostic model predicts overall survival for clear cell renal cell carcinoma and it is associated with immune infiltration

Qianwei Xing, Jiaochen Luan, Shouyong Liu, Limin Ma, Yi Wang
Altered molecular pathways and prognostic markers in active systemic juvenile idiopathic arthritis: integrated bioinformatic analysis

Yi Ren, Hannah Labinsky, Andriko Palmowski, Henrik Bäcker, Michael Müller, Arne Kienzle
Plasma exosome-derived fragile-site associated tumor suppressor is a powerful predictor of prognosis in patients with ovarian cancer

Renjing Ju, Xiaochun Chen, Shiliang Zhang, Bin Liu, Hao Pei, Fan Tu, Jun Liu, Hao Yu
Development and validation a novel preoperative comprehensive prognostic score based on inflammatory and nutritional score, coagulation indicator and tumor marker in esophageal squamous cell carcinoma

Jifeng Feng, Liang Wang, Xun Yang, Qixun Chen

New and Emerging Medical Entities

COVID-19 associated cranial nerve neuropathy: A systematic review

Josef Finsterer, Fulvio Alexandre Scorza, Carla Scorza, Ana Fiorini
Sustained seroprevalence of SARS-CoV-2 antibodies one year after infection: one of the first COVID-19 cluster cases in Bosnia and Herzegovina

Božo Šušak, Vinka Mikulić, Armina Lazarević, Ivanka Mikulić, Jurica Arapovic

New and Emerging Methods

Construction and validation of a preterm birth risk assessment model using fuzzy analytic hierarchy process Preterm birth risk assessment model using fuzzification

Stavroula Barbounaki, Antigoni Sarantaki

Comments

Selection of optimal therapeutic modality for early-stage extranodal natural killer/T-cell lymphoma patients under the guidance of single-nucleotide polymorphism signature

Zhe-Sheng Chen, Dong-Hua Yang