Calls for papers

30 December 2024

Immune Prediction and Prognostic Biomarkers in Immuno-Oncology

Refining the Immunological Landscape of Cancer

We are pleased to announce a call for papers for a special issue in Biomolecules and Biomedicine titled "Immune Prediction and Prognostic Biomarkers in Immuno-Oncology: Refining the Immunological Landscape of Cancer."

This special issue will focus on the advancements in the field of immuno-oncology, specifically on the identification and validation of immune prediction and prognostic biomarkers that can refine the understanding of the immunological landscape of cancer. The rise of immuno-oncology has revolutionized cancer treatment, but the variability in patient responses necessitates reliable predictive and prognostic biomarkers. With a limited number of biomarkers currently in clinical practice, which can lead to suboptimal treatment choices, this special issue is timely. By focusing on the integration of functional immune profiling, genomic analyses, and tumor microenvironment assessments, we aim to spotlight emerging trends and innovative approaches in biomarker discovery that have the potential to enhance patient outcomes.

Purpose of this thematic issue

The primary aim is to explore the intricate relationship between immune biomarkers, tumor biology, and patient outcomes, thereby advancing personalized medicine strategies in oncology. Further, the objectives are to present recent research identifying novel immune-related biomarkers, discuss the influence of tumor microenvironmental factors on immune response and treatment efficacy, and integrate genetic and immune profiling data to enhance biomarker discovery.

Guest editor

Dr. Ziheng Wang
University of Macau, Avenida da Universidade, Taipa, Macau, China

Featured topics

  • Discovery and validation of novel immune biomarkers
  • Impact of the tumor microenvironment on immunotherapy responses
  • Analysis of local and systemic immune responses in the context of cancer treatment

Preferred types of submissions

  • Original Research Articles
  • Review Articles
  • Brief Communications

Why should you publish in a Thematic Issue?

  • Higher Visibility: Thematic articles are collectively published, ensuring broad recognition and visibility within the research community.
  • Frequent Citations: Thematic issues attract more downloads and citations, promoting the impact and reach of your work.
  • Rigorous Peer Review: Each submission undergoes thorough evaluation by at least two independent experts, ensuring the highest standards of quality and clinical relevance.

Submission Guidelines

Submissions should demonstrate originality, methodological rigor, and clear relevance to the thematic issue topics. Authors are encouraged to highlight the translational potential of their findings and their contribution to advancing precision medicine.

Submission period: 1 January 2025 – 30 December 2025

Instructions for submitting your article:

  1. Cover Letter: State that you are submitting your article for the thematic issue on “Immune Prediction and Prognostic Biomarkers in Immuno-Oncology.”
  2. Section Selection: When submitting, select the “Thematic issue: Prognostic and predictive biomarkers in immuno-oncology” section.
  3. Submit Your Article: Follow the journal’s online submission steps: Submit your article

We look forward to receiving your valuable contributions to this special issue, which aims to advance the field of immuno-oncology and refine therapeutic strategies in cancer care.

19 December 2024

Artificial Intelligence and Machine Learning in disease diagnosis and treatment target identification

We are pleased to announce a call for papers for our upcoming thematic issue focusing on the applications of artificial intelligence (AI) and machine learning (ML) in identifying biomarkers and enhancing disease diagnosis and treatment strategies. This thematic issue aims to spotlight emerging research, technological innovations, and clinical insights that leverage computational approaches to improve the early detection, classification, and personalized management of cancer and inflammatory diseases.

With the ongoing expansion of genomic and proteomic data and the increasing adoption of precision medicine, AI and ML have become indispensable tools for integrating high-dimensional datasets, refining diagnostic markers, and streamlining therapeutic decision-making. By uniting experts across biology, data science, and clinical practice, this thematic issue seeks to advance our understanding of how AI-driven models can uncover novel biomarkers, guide targeted therapies, and ultimately improve patient outcomes.

Guest editor

Prof. Dr. Jibin Liu
Affiliated Tumor Hospital of Nantong University, Nantong, China
Contact: tians2008@ntu.edu.cn

Featured Topics

  • Innovations in AI and ML for Biomarker Discovery: Novel algorithms, frameworks, and computational strategies for identifying diagnostic and prognostic biomarkers in cancer and inflammatory diseases.
  • Diagnostic Marker Development: Case studies showcasing successful application of machine learning tools to enhance early disease detection and stratify patient risk profiles.
  • Comparative Approaches: Evaluations of traditional biomarker identification methods versus AI- and ML-driven approaches, highlighting improvements in accuracy, speed, and scalability.
  • Integrative Omics and Clinical Data: AI-enabled models that integrate genomic, proteomic, and clinical datasets to achieve comprehensive disease profiling and uncover hidden molecular signatures.
  • Challenges and Ethical Considerations: Discussions on data privacy, bias mitigation, regulatory frameworks, and best practices in implementing AI technologies in clinical settings.
  • Future Directions in Precision Medicine: Emerging trends, methodologies, and perspectives on how AI and ML will shape personalized diagnosis, therapy selection, and healthcare delivery.

Purpose of this thematic issue

This thematic issue aims to forge stronger links between computational science and biomedical research by illustrating how AI and ML can revolutionize disease diagnosis, prognostication, and targeted therapy development. By highlighting cutting-edge studies, we hope to inform clinical practice, spark interdisciplinary collaboration, and guide future research directions in biomarker discovery and precision medicine. Ultimately, we seek to inspire innovative approaches that will help alleviate the global burden of cancer and inflammatory diseases.

Preferred types of submissions

  • Original Research Articles: Novel mechanistic insights, data-driven biomarker discovery studies, and clinical trial results integrating AI and ML.
  • Review Articles: Comprehensive syntheses of recent advances and expert perspectives on emerging computational approaches and their clinical relevance.
  • Brief Communications: Pilot studies, preliminary findings, and innovative technological proofs-of-concept that highlight the potential of AI and ML in improving patient care.

Why should you publish in a Thematic Issue?

  • Higher Visibility: Thematic articles are collectively published, ensuring broad recognition and visibility within the research community.
  • Frequent Citations: Thematic issues attract more downloads and citations, promoting the impact and reach of your work.
  • Rigorous Peer Review: Each submission undergoes thorough evaluation by at least two independent experts, ensuring the highest standards of quality and clinical relevance.

Submission Guidelines

Submissions should demonstrate originality, methodological rigor, and clear relevance to the development or application of AI and ML in disease diagnosis and treatment target identification. Authors are encouraged to highlight the translational potential of their findings and their contribution to advancing precision medicine.

Submission period: 1 January 2025 – 30 December 2025

Instructions for submitting your article:

  1. Cover Letter: State that you are submitting your article for the thematic issue on “Applications of Artificial Intelligence and Machine Learning in Disease Diagnosis and Treatment Target Identification.”
  2. Section Selection: When submitting, select the “Thematic issue: AI/ML in diseases” section.
  3. Submit Your Article: Follow the journal’s online submission steps: Submit your article
  4. Contact the Guest Editor: For inquiries or to inform of your intention to submit, contact Prof. Dr. Jibin Liu (tians2008@ntu.edu.cn).

Join us in shaping the future of biomarker research, personalized medicine, and healthcare delivery. By contributing your groundbreaking research, you will help advance the frontier of AI- and ML-driven diagnostics and therapeutics, and foster a new era of patient-centered care.

17 December 2024

Insulin for Type 1 and Type 2 Diabetes Mellitus

Pathophysiology, Complications and Treatment

We announce a call for papers for our upcoming thematic issue focusing on insulin in the management of Type 1 and Type 2 diabetes mellitus. This issue seeks to highlight cutting-edge research and clinical insights on the pathophysiology, complications, and treatment approaches related to insulin therapy. With diabetes being a leading global health challenge, this thematic issue aims to present advanced strategies to enhance diagnosis, improve glycemic control, and mitigate long-term complications through innovative therapies, exercise and dietary interventions, novel biomarkers, and next-generation pharmacological and technological solutions.

Download the full thematic issue description here.

Guest editor

Prof. Dr. Georgios Panoutsopoulos
Department of Nutrition and Health Sciences, University of Peloponnese, Tripoli, Greece

Featured Topics

  • Pathophysiology of Type 1 and Type 2 Diabetes: Mechanistic insights into insulin resistance, β-cell dysfunction, and disease progression.
  • Diagnostic Advances: Novel biomarkers, continuous glucose monitoring technologies, and early detection methods.
  • Insulin Therapy and Action: Latest developments in insulin formulations, insulin analogues, delivery systems, and strategies for optimizing insulin’s efficacy.
  • Cardiovascular and Microvascular Complications: Exploring the links between hyperglycemia, insulin resistance, atherosclerosis, and organ-specific complications (kidney, retina, nervous system).
  • Therapeutic Innovation: Pharmacological approaches, oral hypoglycemic agents, gene therapy, and stem cell-based interventions aimed at β-cell regeneration and improved metabolic flexibility.
  • Lifestyle Interventions: The role of exercise, nutritional strategies, and non-pharmacological treatments in enhancing glycemic control and reducing complications.
  • Emerging Trends: Novel concepts such as the gut microbiota’s role, inflammation, mitochondrial dysfunction, and metabolic syndrome as they relate to insulin action and diabetes management.

Purpose of this thematic issue

This Thematic issue aims to integrate basic, translational, and clinical research to advance our understanding of insulin’s role in diabetes. By highlighting cutting-edge studies and evidence-based interventions, we hope to pave the way for improved patient outcomes and inform future clinical practice guidelines. Ultimately, we seek to inspire innovative research avenues that can reduce the global burden of diabetes and its associated dysfunctions.

Preferred types of submissions

  • Original research articles presenting novel mechanistic insights or clinical trial data.
  • Review articles synthesizing recent advances and offering expert perspectives on emerging topics.
  • Brief communications showcasing promising pilot studies, innovative technologies, or preliminary findings.

Why should you publish in a Special Issue?

  • Thematic issue articles are collectively published, significantly boosting visibility and discoverability.
  • They are downloaded and cited more frequently, ensuring broad recognition of your work.
  • Each submission undergoes rigorous peer review by at least two independent experts, ensuring quality, originality, and clinical relevance.

Submission Guidelines

Submissions should demonstrate originality, clear relevance to diabetes research and insulin-related treatments, methodological rigor, and adherence to ethical standards. Authors are encouraged to highlight the novelty or translational potential of their findings or, in the case of reviews, provide personal viewpoints on emerging topics.

Submission period: 1 January 2025 - 30 June 2025

Instructions for submitting your article:

  1. Cover letter: State that you are submitting your article for the Thematic issue on “Insulin for Type 1 and Type 2 Diabetes Mellitus: Pathophysiology, Complications and Treatment.”
  2. Section selection: When submitting your article, choose the “Thematic issue: Insulin and Diabetes” section.
  3. Submit your article: Follow the journal’s online submission steps: Submit your article
    Before submission, you may also contact the Guest Editor (Prof. Dr. Georgios Panoutsopoulos: gpanouts@uop.edu.gr) to inform them of your intention to submit.

Join us in advancing the understanding and clinical management of diabetes by contributing your groundbreaking research to this Thematic issue. Your work will be rigorously reviewed by leading experts and receive broad recognition within the scientific community.

15 June 2024

Cell-based Therapeutics

We announce a call for papers for our upcoming special issue focusing on Cell-Based Therapeutics. This issue aims to showcase the transformative impacts of cell-based therapies on clinical practice and the pharmaceutical industry, featuring innovative treatments like genetically reprogrammed T cells for lymphoid cancers and adipose-derived stem cells for Crohn’s disease.

Editors

  • Yan Ma, Research Associate, Spatial Navigation and Memory Unit, National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH), Maryland, USA.
  • Dr. Meijie Tian, NIH-funded researcher, Oncogenomic section, Genetics Branch, Center of Cancer Research, National Cancer Institute (NCI).
  • Dr. Mohd Hussain Shah, Ophthalmology Department, Ohio State University; current research fellow at National Eye Institute (NEI).

Featured Topics

  • Targeted Delivery and Biodistribution: How cell-based therapies utilize cellular properties for precise therapeutic delivery.
  • Advanced Sense-and-Response Functions: The dynamic capabilities of these therapies to monitor and respond to disease states.
  • Sustained Endogenous Drug Delivery: Exploring the persistence and long-term benefits of therapeutic cells in vivo.
  • Challenges and Solutions: Addressing the hurdles in adoption and commercialization, including cell source stability, safety, and scalable manufacturing processes.
  • Next-Generation Engineering Approaches: We are particularly interested in manuscripts discussing innovative engineering approaches such as genome and epigenome editing, synthetic biology, and biomaterial-mediated immune modulation that enhance therapeutic efficacy and address current limitations.

Purpose of This Special Issue

Our goal is to bridge the gap between basic and clinical research, enhancing the translation of groundbreaking research into clinical applications. We are looking for submissions that discuss novel methods in cell collection, isolation, modification, and production, as well as clinical applications focusing on safety, efficacy, and regulatory compliance.

Preferred Types of Submissions

  • Original studies on the characterization and utilization of therapeutic cells.
  • Reviews on molecular strategies enhancing cell-based therapeutic functions.
  • Brief communications on novel technologies and approaches in cell production.

Why should you publish in a Special Issue?

  • Articles in a Special Issue are collectively published significantly enhancing their visibility and discoverability by other researchers.
  • Special Issue content is downloaded twice as frequently compared to articles in regular issues.
  • Special Issue articles receive 20% more citations in the same period than those published in standard issues.
  • Each submission to this Special Issue will undergo rigorous peer review by a minimum of two independent experts, ensuring the quality, originality, and novelty of the published work.

Submission Guidelines

Submissions should demonstrate originality, relevance to genetic research and biotechnological applications, rigorous methodology, and compliance with ethical standards.

Submission Period: 15 June 2024 to 15 June 2025

Instructions for submitting the article

1. Write a Cover letter: State that you are submitting your article for the special issue on Cell-Based Therapeutics.
2. Select the correct Section: When submitting your article, choose the "Cell-Based Therapies" section.
3. Submit your article: Follow the steps on this link to submit your article: Submit your article

Join us in advancing the field of cell-based therapies by contributing your groundbreaking research to this special issue. Your work will be handled by well-known experts in the field, ensuring thorough review and wide recognition.

15 August 2024 - Announcement

Microbiome and Cancer

We are pleased to announce an upcoming call for papers for our special issue on The Microbiome and Cancer (Immunotherapy): Unraveling the Interactions and Therapeutic Potential. This issue will focus on advancing our understanding of the intricate relationship between the microbiome and cancer, particularly in the context of immunotherapy, with the goal of translating these insights into innovative therapeutic approaches.

Objective of This Special Issue

As the field of oncology evolves, the role of the microbiome in influencing cancer development and treatment responses is increasingly recognized as a pivotal area of research. This special issue aims to bring together high-quality contributions that explore the molecular mechanisms by which the microbiome modulates immune responses, affects tumor microenvironments, and impacts the efficacy of cancer immunotherapies. Our objective is to provide a comprehensive resource that advances both basic science and clinical applications in this rapidly growing field.

Scope of Submissions

We invite rigorous and impactful submissions that reflect the breadth and depth of research in this area:

  • Original research that provides new insights into the interactions between the microbiome and cancer, with a focus on immunotherapy outcomes.
  • In-depth reviews that critically assess current knowledge and propose future directions for integrating microbiome research into cancer treatment paradigms.
  • Brief communications highlighting novel methodologies or preliminary findings that have the potential to influence future research and therapeutic strategies.

Why Contribute to This Special Issue?

  • Scientific Significance: Contributing to this special issue provides an opportunity to present your research in a field that is at the forefront of cancer treatment innovation.
  • Broad Impact: Your work will be part of a specialized issue aimed at influencing both academic research and clinical practices.
  • Interdisciplinary Collaboration: This issue seeks to foster collaboration between microbiologists, oncologists, immunologists, and other experts, creating a platform for interdisciplinary dialogue and discovery.

We encourage submissions from leading researchers and practitioners who are contributing to the understanding of the microbiome's role in cancer and immunotherapy. Detailed submission guidelines and deadlines will be announced shortly. We look forward to your contributions that will help shape the future of cancer therapy.

30 August 2024 - Announcement

Cell Death: Mechanisms, decisions, and therapeutic approaches

We are excited to announce an upcoming call for papers for a special issue focusing on Cell Death: Mechanisms, Decisions, and Therapeutic Approaches. This issue will delve into the complex processes that govern cell death, exploring how these mechanisms influence disease progression and therapeutic outcomes. By highlighting cutting-edge research in this field, we aim to foster new insights and innovations that could lead to transformative therapies across a range of diseases.

Purpose of This Special Issue

Our goal is to deepen the understanding of cell death mechanisms, bridging fundamental research with clinical applications to develop new therapeutic approaches. We are seeking submissions that investigate the molecular pathways of apoptosis, necrosis, autophagy, and other cell death processes, and how these can be modulated for therapeutic benefit. Additionally, we welcome studies that explore the implications of cell death in disease progression and therapy, offering insights into how these processes can be harnessed or inhibited in clinical settings.

Preferred Types of Submissions

  • Original studies on the molecular mechanisms driving different forms of cell death and their implications in diseases.
  • Reviews on the latest therapeutic strategies targeting cell death pathways, including small molecules, biologics, and gene therapies.
  • Brief communications on novel techniques for modulating cell death in preclinical and clinical settings, as well as innovative therapeutic approaches aimed at controlling cell fate.

Why Should You Publish in a Special Issue?

Publishing in a Special Issue offers a unique opportunity to maximize the impact of your research while benefiting from a streamlined process. Here’s why submitting to a Special Issue is an excellent choice for your work:

  1. Enhanced Visibility and Discoverability:

    • Articles in Special Issues are part of a themed collection that naturally draws the attention of researchers and practitioners interested in the specific topic. This targeted focus ensures that your work is more visible and discoverable by the right audience.
    • Special Issues are frequently highlighted by journals, further increasing the prominence of your article. This collective publication approach significantly boosts your research’s exposure.

  2. Increased Downloads and Citations:

    • Higher Download Rates: Special Issue articles are downloaded twice as frequently compared to those in regular issues, reflecting the relevance and interest of the focused topic. This increased engagement amplifies the reach of your work.
    • More Citations: On average, Special Issue articles receive 20% more citations within the same period than articles published in standard issues. By contributing to a Special Issue, you enhance your research's visibility and citation potential, which is crucial for building your academic reputation.

  3. Rigorous and Quick Peer Review Process:

    • Submissions to the Special Issue undergo a rigorous peer review process by at least two independent experts. This ensures that only high-quality, original, and novel research is published.
    • Faster Turnaround: The entire process, from submission to publication, is designed to be quick and efficient. Special Issues often operate on an accelerated timeline, immediately after acceptance ensuring that your research reaches the academic community without unnecessary delays. You can expect timely feedback and a smooth publication process.

We encourage researchers and clinicians to prepare their submissions for this upcoming issue and contribute to advancing the field of cell death research and its therapeutic applications. Stay tuned for further details on submission deadlines and publication dates.