Clear cell urothelial carcinoma of the urinary bladder - a rare pathological entity. A case report and a systematic review of the literature

Ioana Mihai; Sorina Taban; Alin Cumpanas; Emilian Gh. Olteanu; Mihaela Iacob; Alis Dema

doi:10.17305/bjbms.2019.4182

Authors

Ioana Mihai Department of Morphopathology, The Victor Babes University of Medicine and Pharmacy of Timisoara, Timisoara, Romania https://orcid.org/0000-0003-0617-4178
Sorina Taban Department of Morphopathology, The Victor Babes University of Medicine and Pharmacy of Timisoara; Department of Pathology, Emergency Clinical County Hospital Pius Brinzeu, Timisoara, Romania
Alin Cumpanas Department of Urology, The Victor Babes University of Medicine and Pharmacy of Timisoara; Department of Urology, Emergency Clinical County Hospital Pius Brinzeu, Timisoara, Romania
Emilian Gh. Olteanu Department of Morphopathology, The Victor Babes University of Medicine and Pharmacy of Timisoara; Department of Pathology, Emergency Clinical County Hospital Pius Brinzeu; Centre for Gene and Cellular Therapies in Cancer - Oncogen, Timisoara, Romania https://orcid.org/0000-0001-5921-4634
Mihaela Iacob Department of Pathology, Emergency Clinical County Hospital Pius Brinzeu, Timisoara, Romania
Alis Dema Department of Morphopathology, The Victor Babes University of Medicine and Pharmacy of Timisoara; Department of Pathology, Emergency Clinical County Hospital Pius Brinzeu, Timisoara, Romania https://orcid.org/0000-0003-0767-2718

DOI:

https://doi.org/10.17305/bjbms.2019.4182

Keywords:

clear cell urothelial carcinoma, urinary bladder, review

Abstract

The most common histological type of urinary bladder cancer is urothelial carcinoma (UC). In contrast, the clear cell variant of urothelial carcinoma (CCUC) is quite a rare neoplasm. In this study, we report a case of an 81-year-old male, presenting with gross hematuria and acute urinary retention, which was subsequently diagnosed with CCUC at our pathology department. Furthermore, we provide a short systematic review of the literature (PubMed, Scopus, and Science Citation Index) for this rare histopathological entity and a brief discussion about its morphological and immunohistochemical (IHC) characteristics.