Increased coronary intervention rate among diabetic patients with poor glycaemic control: a cross-sectional study

  • Süha Çetin Department of Cardiology, 29 Mayıs Hospital
  • Mehmet Akif Öztürk Department of Internal Medicine, School of Medicine, Gazi University
  • Nadir Barındık Department of Cardiology, 29 Mayıs Hospital
  • Ersin İmren Department of Cardiology, 29 Mayıs Hospital
  • Yüksel Peker Department of Molecular and Clinical Medicine/Cardiology, Sahlgrenska Academy, University of Gothenborg
Keywords: Diabetes mellitus, glycaemic control, coronary artery disease, revascularization

Abstract

The relationship between glycaemic control and coronary artery disease (CAD) in type 2 diabetes mellitus (T2DM) is controversial. In the current cross-sectional study, we addressed the relationship between Hemoglobin A1c (HbA1c) values and the need for revascularization among diabetic patients undergoing coronary angiography. A total of 301 consecutive patients with known T2DM (age 61.8±10.1 years, 46.2 % women) requiring coronary angiography due to CAD symptoms were included. T2DM patients were categorized into two groups based on their HbA1c values: 93 (30.9%) diabetics with good glycaemic control (HbA1c≤7 %), and 208 (69.1%) diabetics with poor glycaemic control(HbA1c>7 %). A total of 123 patients (40.9%) required revascularization. The revascularization rate was 28.0% among T2DM patients with good glycaemic control and 46.6% among T2DM patients with poor glycaemic control, respectively (p=0.002). In a logistic regression analysis, the need for revascularization was predicted by poor glycaemic control (Odds Ratio [OR] 2.26, 95% Confidence Interval [CI] 1.32-3.82; p=0.003) adjusted for age, gender, Body-Mass-Index and diabetes duration. Moreover, there was a linear relationship between HbA1c values and number of affected coronary arteries (r= 0.169; p=0.003). Our data suggest that there is a close association between poorglycaemic control and increased revascularization rate in T2DM, which should be considered in primary and secondary prevention models.

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Increased coronary intervention rate among diabetic patients with poor glycaemic control: a cross-sectional study
Published
2014-05-20
How to Cite
1.
Çetin S, Akif Öztürk M, Barındık N, İmren E, Peker Y. Increased coronary intervention rate among diabetic patients with poor glycaemic control: a cross-sectional study. Bosn J of Basic Med Sci [Internet]. 2014May20 [cited 2020Aug.7];14(1):16-0. Available from: https://bjbms.org/ojs/index.php/bjbms/article/view/2286
Section
Translational and Clinical Research