The osteoplastic effectiveness of the implants made of mesh titanium nickelide constructs

Iurii Mikhailovich Irianov; Olga Vladimirovna Diuriagina; Tatiana Iurevna Karaseva; Evgenii Anatolevich Karasev

doi:10.17305/bjbms.2014.2284

Authors

Iurii Mikhailovich Irianov Laboratory of Morphology, Russian Ilizarov Scientific Center Restorative Traumatology and Orthopaedics (RISC RTO)
Olga Vladimirovna Diuriagina Laboratory of Purulent Osteology and Limb Defect Filling, RISC RTO
Tatiana Iurevna Karaseva Department of Orthopaedics, Russian Ilizarov Scientific Center Restorative Traumatology and Orthopaedics (RISC RTO)
Evgenii Anatolevich Karasev Department of Orthopaedics, Russian Ilizarov Scientific Center Restorative Traumatology and Orthopaedics (RISC RTO)

DOI:

https://doi.org/10.17305/bjbms.2014.2284

Keywords:

implant, titanium nickelide, bone defect, reparative osteogenesis

Abstract

The purpose of the work was to study the features of reparative osteogenesis for filling the defect of tubular bone under implantation of meshtitanium nickelide constructs. Tibial fenestrated defect was modeled experimentally in 30 Wistar pubertal rats, followed by implant intramedullary insertion. The techniques of radiography, scanning electron microscopy and X-ray electron probe microanalysis were used. The mesh implant of titanium nickelide has been established to possess biocompatibility, osteoconductive and osteoinductive properties, the zone of osteogenesis and angiogenesis is created around it, bone cover is formed. Osteointegration of the implant occurs early, by 7 days after surgery, and by 30 days after surgery organotypical re-modelling of the regenerated bone takes place, as well as the defect is filled with lamellar bone tissue by the type of bone wound primary adhesion. By 30 days after surgery mineral content of the regenerated bone tissue approximates to the composition of intact cortex mineral phase.