Left ventricular mechanics in Behcet’s disease: A speckle tracking echocardiographic study

  • Selami Demirelli Department of Cardiology, Erzurum Education and Research Hospital, Erzurum
  • Hüsnü Degirmenci Department of Cardiology, Erzincan University, Erzincan
  • Handan Bilen Department of Dermatology, Faculty of Medicine, Atatürk University, Erzurum
  • Emrah Ermis Department of Cardiology, Erzurum Education and Research Hospital, Erzurum
  • Hakan Duman Department of Cardiology, Erzurum Education and Research Hospital, Erzurum
  • Arif Arisoy Department of Cardiology, Corum Education and Research Hospital, Corum
  • Eftal Murat Bakirci Department of Cardiology, Erzincan University, Erzincan
  • Emrah Ipek Department of Cardiology, Erzurum Education and Research Hospital, Erzurum
  • Lutfu Askin Department of Cardiology, Erzurum Education and Research Hospital, Erzurum
Keywords: Behcet’s disease, speckle tracking echocardiyography, torsion, rotation

Abstract

Although cardiac involvement is rarely seen in Behcet’s disease (BD), it is essential to detect subclinical left ventricular (LV) dysfunction for prognostic purposes. Herein we aimed to show the role of two dimensional (2D) speckle tracking echocardiography (STE) in determination of  subclinical LV dysfunction in patients with BD. 30 patients diagnosed as BD due to International Study Group Behcet’s diagnostic criteria and 25 control subjects underwent Doppler echocardiography including pulsed tissue Doppler of the mitral annulus and speckle-tracking echocardiography. LV peak longitudinal strain and strain rate (SR) was calculated in four-chamber (4C), apical long-axis (LAX), and two-chamber (2C) views, and values of the three views were averaged LV global longitudinal strain (LV-GLS) and SR. LV torsion was determined as the net difference in the mean rotation between the apical and basal levels. There was not any significant difference in age and gender between groups. Patients with BD had significantly lower LV longitudinal strain and Sr measurements than the control group. Although LV basal rotation (LVR) basal values were similar in both groups, LVR-apical and LV torsion (LVTR) values were significantly higher in patient group. LVR-apical and LV-GLS were found to have a good positive corelation (r:0.44, p<0.001) (r: -0.56, r: -0.65,respectively. p<0.001). There was a weak positive correlation between LVTR and LV-GLS (r: 0.29, p<0.05). We demonstrated that combined assessement of LV-GLS, LV-GLSR, LVTR and LVR-apical values detected by STE can be useful in determination of subclinical left ventricular dysfunction in BD.

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Author Biography

Selami Demirelli, Department of Cardiology, Erzurum Education and Research Hospital, Erzurum
Cardiology

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Published
2014-08-15
How to Cite
1.
Demirelli S, Degirmenci H, Bilen H, Ermis E, Duman H, Arisoy A, Bakirci EM, Ipek E, Askin L. Left ventricular mechanics in Behcet’s disease: A speckle tracking echocardiographic study. Bosn J of Basic Med Sci [Internet]. 2014Aug.15 [cited 2019Dec.9];14(3):160-4. Available from: http://bjbms.org/ojs/index.php/bjbms/article/view/160
Section
Translational and Clinical Research